Design and Characterization of Apocynin Loaded PLGA Nanoparticles and their In vivo Efficacy in Hyperoxaluric Rats.

@article{Sharma2018DesignAC,
  title={Design and Characterization of Apocynin Loaded PLGA Nanoparticles and their In vivo Efficacy in Hyperoxaluric Rats.},
  author={Satvika Sharma and Ankush Parmar and Rishi Bhardwaj and Rakesh Kumar Bijarnia and Tanzeer Kaur},
  journal={Current drug delivery},
  year={2018},
  volume={15 7},
  pages={
          1020-1027
        }
}
BACKGROUND Apocynin has become a drug of choice in NADPH oxidase induced pathological conditions. Hyperoxaluria is one such pathological condition where NADPH oxidase is involved in eliciting renal injury. OBJECTIVE Recently apocynin has shown to reverse the transcriptome profile of the NADPH oxidaseassociated genes and reduced oxidative burden in… CONTINUE READING