Design Space Approach in Optimization of Fluid Bed Granulation and Tablets Compression Process

@inproceedings{Djuri2012DesignSA,
  title={Design Space Approach in Optimization of Fluid Bed Granulation and Tablets Compression Process},
  author={Jelena Djuri{\vs} and Djordje P. Medarevi{\'c} and Marko Krstic and Ivana Vasiljevi{\'c} and Ivana Ma{\vs}i{\'c} and Svetlana Ibric},
  booktitle={TheScientificWorldJournal},
  year={2012}
}
The aim of this study was to optimize fluid bed granulation and tablets compression processes using design space approach. Type of diluent, binder concentration, temperature during mixing, granulation and drying, spray rate, and atomization pressure were recognized as critical formulation and process parameters. They were varied in the first set of… CONTINUE READING