• Corpus ID: 13046876

Design , Synthesis , Characterization and Antimicrobial Evaluation of Novel 2 , 4-Disubstituted Quinazoline Derivatives

@inproceedings{Deshpande2017DesignS,
  title={Design , Synthesis , Characterization and Antimicrobial Evaluation of Novel 2 , 4-Disubstituted Quinazoline Derivatives},
  author={Anant N. Deshpande and Shashikant C. Dhawale},
  year={2017}
}
Resistance to bacterial and fungal strains towards existing antimicrobial agents has become an increasing incietment for research and development of new molecules to guard them. Quinazoline ring system could be clubbed into many ring systems which lead to potent and highly active compounds. In this work, series of eighteen compounds were docked into the ecKAS III binding site (1HNJ, PDB ID) by using schrodinger software. Out of which, six derivatives showed highest glide score. A simple method… 
1 Citations

Figures and Tables from this paper

Evaluation of antibacterial and antifungal activities of N-benzylthienopyrimidinone derivatives
This study is part of the biological investigation of the chemical library of molecules already described by the Laboratory of Organic Chemistry and Therapeutic Chemistry of the University of

References

SHOWING 1-10 OF 23 REFERENCES
"J."
however (for it was the literal soul of the life of the Redeemer, John xv. io), is the peculiar token of fellowship with the Redeemer. That love to God (what is meant here is not God’s love to men)
Chem
  • Biol.
  • 2007
De-Yu Hu; IH Jin; BA Song; S Yang; PS Liu; PS Bhadury; Y Ma; H Luo; X
  • Zhou. Bioorg. Med. Chem.
  • 2007
Int
  • J. Pharm. Sci. Res.
  • 2016
Pakkath; KR Haridas
  • SN Kumari; Eur. J. Med. Chem.,
  • 2014
Indian J
  • Chem.
  • 2015
Med
  • Chem. Res.
  • 2015
Bioorg
  • Med. Chem.
  • 2014
Bioorg
  • Med Chem.
  • 2009
Bioorg
  • Med. Chem.
  • 2009
...
...