Design, synthesis and evaluation of antitumor activity of new rotundic acid acylhydrazone derivatives.

Abstract

In light of the important antitumor activity of acylhydrazone compounds and based on our previous study, 18 new rotundic acid (RA) acylhydrazone derivatives were synthesized. All of the compounds were characterized by their spectroscopic data. The antiproliferative activity of the compounds was evaluated in vitro via the MTT method in three tumor cell lines… (More)
DOI: 10.1515/znc-2015-0119

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