Design, synthesis and biological evaluation of novel lipoamino acid-based glycolipids for oral drug delivery.

  title={Design, synthesis and biological evaluation of novel lipoamino acid-based glycolipids for oral drug delivery.},
  author={R. Falconer and I. Toth},
  journal={Bioorganic \& medicinal chemistry},
  volume={15 22},
A series of lipoamino acid-based glycolipids were synthesised. Suitably derivatised lipoamino acid derivatives were prepared and conjugated to monosaccharides (including glycosyl azides, isothiocyanates, thiols and sulphones) to yield novel O-, N-, S- and C-linked glycolipids in good yields. Their potential to improve the oral absorption of piperacillin is reported. 
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  • 1994
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