Design, synthesis and anticancer activity evaluation of some novel pyrrolo[1,2-a]azepine derivatives.

Abstract

A novel series of pyrrolo[1,2-a]azepine derivatives 3-7 were synthesized and their structures were confirmed by spectral and elemental analyses. Antitumor activity evaluation of these compounds was carried out against liver (HepG2), breast (MCF7), and colon (HCT116) cancer cell lines using the sulforhodamine-B (SRB) assay method and doxorubicin as reference… (More)
DOI: 10.1002/ardp.201400004

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