Design, synthesis and anti-leishmanial activity of novel symmetrical bispyridinium cyclophanes.


Nine novel symmetrical bispyridinium cyclophanes have been synthesized. They are rigid derivatives with an upper spacer which joins the two exocyclic amino groups, and a lower spacer joining the two positively charged nitrogen atoms. At least one of the two spacers is an aliphatic linker, such as an alkane or oxyalkane fragment. The activity of these… (More)
DOI: 10.1016/j.ejmech.2014.10.040


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