Design, development and production of nano-particle-based anticancer vaccine targeting human aspartyl (asparaginyl) β-hydroxylase (HAAH)

Abstract

HAAH is a protein that is over-expressed in cancer cells and is presented on the surface of the cells and in the growth zone of the tumors. It plays a central role in the etiology of cancer, namely, in proliferation, motility and invasion. It is, however, an embryonic protein important during development and, as such, is a self protein to which the immune… (More)

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