Design, Synthesis and Anticancer Activity of Aza Heterocycles Containing Gallate Moiety (Part III)

Abstract

Our previously reported compound, 3-(2-hydroxy-3,4-dimethoxyphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde (1), was allowed to react with acetophenone, ethyl cyanoacetate and/or malononitrile to give the corresponding compounds 2a, 2b and 2c, respectively. Treatment of compounds 2b and 2c with thiourea afforded thiopyrimidine derivatives 3a and 3b… (More)
DOI: 10.1007/s11094-017-1554-y

Topics

3 Figures and Tables