Design, Optimization and Characterisation of Polymeric Microneedle Arrays Prepared by a Novel Laser-Based Micromoulding Technique

@article{Donnelly2010DesignOA,
  title={Design, Optimization and Characterisation of Polymeric Microneedle Arrays Prepared by a Novel Laser-Based Micromoulding Technique},
  author={Ryan F Donnelly and Rita J. Majithiya and Thakur Raghu Raj Singh and Desmond I. J. Morrow and Martin James Garland and Yusuf Kemal Demir and Katarzyna Migalska and Elizabeth M Ryan and David Gillen and Christopher James Scott and A. David Woolfson},
  journal={Pharmaceutical Research},
  year={2010},
  volume={28},
  pages={41-57}
}
Design and evaluation of a novel laser-based method for micromoulding of microneedle arrays from polymeric materials under ambient conditions. The aim of this study was to optimise polymeric composition and assess the performance of microneedle devices that possess different geometries. A range of microneedle geometries was engineered into silicone micromoulds, and their physicochemical features were subsequently characterised. Microneedles micromoulded from 20% w/w aqueous blends of the… CONTINUE READING