Desiccated thyroid extract compared with levothyroxine in the treatment of hypothyroidism: a randomized, double-blind, crossover study.

@article{Hoang2013DesiccatedTE,
  title={Desiccated thyroid extract compared with levothyroxine in the treatment of hypothyroidism: a randomized, double-blind, crossover study.},
  author={Thanh D. Hoang and C. Olsen and V. Q. Mai and Patrick W. Clyde and M. Shakir},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2013},
  volume={98 5},
  pages={
          1982-90
        }
}
CONTEXT Patients previously treated with desiccated thyroid extract (DTE), when being switched to levothyroxine (L-T₄), occasionally did not feel as well despite adequate dosing based on serum TSH levels. OBJECTIVE Our objective was to investigate the effectiveness of DTE compared with L-T₄ in hypothyroid patients. DESIGN AND SETTING We conducted a randomized, double-blind, crossover study at a tertiary care center. PATIENTS Patients (n = 70, age 18-65 years) diagnosed with primary… Expand
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