Desflurane and isoflurane exert modest beneficial actions on left ventricular diastolic function during myocardial ischemia in dogs.

@article{Pagel1995DesfluraneAI,
  title={Desflurane and isoflurane exert modest beneficial actions on left ventricular diastolic function during myocardial ischemia in dogs.},
  author={Paul S. Pagel and Douglas A. Hettrick and Donald Lowe and John P. Tessmer and David C. Warltier},
  journal={Anesthesiology},
  year={1995},
  volume={83 5},
  pages={
          1021-35
        }
}
BACKGROUND Volatile anesthetics exert cardioprotective effects during myocardial ischemia. This investigation examined the regional systolic and diastolic mechanical responses to brief left anterior descending coronary artery (LAD) occlusion in the central ischemic zone and in remote normal myocardium in the conscious state and during desflurane and isoflurane anesthesia. METHODS Eighteen experiments were performed in nine dogs chronically instrumented for measurement of aortic and left… CONTINUE READING
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