Desflurane anaesthesia increases sister chromatid exchanges in human lymphocytes.

BACKGROUND We investigated genotoxic effects of desflurane on the frequency of sister chromatid exchange (SCE) in peripheral blood lymphocytes of patients during and after anaesthesia. METHODS Fifteen female patients, ASA classification I-II, aged 26-54 years, undergoing elective surgery were enroled in this study. Anaesthesia was induced by injection of… CONTINUE READING