Desensitization of the dopaminergic inhibition of pituitary luteinizing hormone release by prolactin in ovariectomized rats.

@article{Beck1977DesensitizationOT,
  title={Desensitization of the dopaminergic inhibition of pituitary luteinizing hormone release by prolactin in ovariectomized rats.},
  author={Wolf Beck and Wolfgang Wuttke},
  journal={The Journal of endocrinology},
  year={1977},
  volume={74 1},
  pages={67-74}
}
Increase of plasma prolactin in chronically ovariectomized rats by transplanting pituitary glands from male rats to the kidney capsule reduced pituitary LH output for 1 week. At the end of this time, despite the fact that prolactin remained high, plasma LH levels rose to reach the value seen in ovariectomized control rats. High plasma prolactin did not affect FSH concentrations. Treatment of ovariectomized rats with apomorphine, a dopamine-receptor stimulating drug, reduced pituitary LH release… CONTINUE READING