New members of the spider family Caponiidae from Brazil and Chile are presented. Three new species in previously known genera are described: Taintnops papososp. n. from Chile, and the Brazilian Tisentnops mineirosp. n. and Tisentnops onixsp. n., both belonging to a genus known only from its damaged type. Additionally, two new non-nopine Brazilian genera are proposed: Nasutonopsgen. n. including three new species: Nasutonops chapeusp. n., Nasutonops sincorasp. n. and Nasutonops xaxadosp. n.; and Carajasgen. n., known only from the type species Carajas parauasp. n. Both new genera have entire, rather than sub-segmented tarsi. Therefore, they are not included in the caponiid subfamily Nopinae. Nasutonopsgen. n. is characterized by the presence of a projected clypeal horn, unique among caponiids. Additionally, the first blind caponiids are described: Tisentnops mineirosp. n. from the state of Minas Gerais and Carajas parauasp. n. from the state of Pará. Both of these species are found only in caves and completely lack eyes.