Description of a new monoclonal antibody, FC-2.15, reactive with human breast cancer and other human neoplasias.

@article{Mordoh1994DescriptionOA,
  title={Description of a new monoclonal antibody, FC-2.15, reactive with human breast cancer and other human neoplasias.},
  author={Jos{\'e} Mordoh and Stefan Leis and Alicia In{\'e}s Bravo and Osvaldo L. Podhajcer and Cecilia Ballar{\'e} and Mariana Capurro and Claudia Kairiyama and Laura Bover},
  journal={The International journal of biological markers},
  year={1994},
  volume={9 3},
  pages={125-34}
}
FC-2.15 is an IgM monoclonal antibody (MAb) obtained by immunizing Balb/c mice with tumor epithelial cells from a human undifferentiated primary breast carcinoma. FC-2.15 reacts with 93.9% (31/33) of human breast primary tumors, independently of their histology and hormone receptor content. Moreover, FC-2.15 reacts with 79.6 +/- 13.8% (mean +/- SD) of total breast malignant tumor cells and with 88.7 +/- 9.9% of proliferating tumor cells. It recognizes other neoplasia such as colon cancer… CONTINUE READING

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