Description of Parkinson's disease as a clinical syndrome.

  title={Description of Parkinson's disease as a clinical syndrome.},
  author={Stanley Fahn},
  journal={Annals of the New York Academy of Sciences},
  • Stanley Fahn
  • Published 2003 in Annals of the New York Academy of Sciences
Parkinsonism is a clinical syndrome comprising combinations of motor problems-namely, bradykinesia, resting tremor, rigidity, flexed posture, "freezing," and loss of postural reflexes. Parkinson's disease (PD) is the major cause of parkinsonism. PD is a slowly progressive parkinsonian syndrome that begins insidiously and usually affects one side of the body before spreading to involve the other side. Pathology shows loss of neuromelanin-containing monoamine neurons, particularly dopamine (DA… CONTINUE READING
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