Description of 13 Infants Born During October 2015-January 2016 With Congenital Zika Virus Infection Without Microcephaly at Birth - Brazil.

@article{Linden2016DescriptionO1,
  title={Description of 13 Infants Born During October 2015-January 2016 With Congenital Zika Virus Infection Without Microcephaly at Birth - Brazil.},
  author={V. van der Linden and A. Pessoa and W. Dobyns and A. Barkovich and H. V. D. L. J{\'u}nior and Epit{\'a}cio Leite Rolim Filho and E. Ribeiro and M. C. Leal and P. Coimbra and M. Arag{\~a}o and I. Verçosa and C. Ventura and R. Ramos and Danielle Di Cavalcanti Sousa Cruz and M. Cordeiro and V. M. Mota and Mary M Dott and Christina L. Hillard and C. Moore},
  journal={MMWR. Morbidity and mortality weekly report},
  year={2016},
  volume={65 47},
  pages={
          1343-1348
        }
}
Congenital Zika virus infection can cause microcephaly and severe brain abnormalities (1). Congenital Zika syndrome comprises a spectrum of clinical features (2); however, as is the case with most newly recognized teratogens, the earliest documented clinical presentation is expected to be the most severe. Initial descriptions of the effects of in utero Zika virus infection centered prominently on the finding of congenital microcephaly (3). To assess the possibility of clinical presentations… Expand
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Severe neurodevelopmental delay, severe microcephaly, epileptic seizures and dysphagia were present at 2 years of age in most CZS cases of the 21 children with congenital ZIKV infection born in Ecuador who were followed up until September 2019. Expand
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The temporal association between reported Zika virus infections and the occurrence of microcephaly, with the peak number of reported microcePHaly cases occurring approximately 24 weeks after the peak of the Zika virus disease outbreak, provides evidence suggesting that the period of highest risk is during the first trimester of pregnancy and early in the second trimesterof pregnancy. Expand
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Clinical manifestations can appear after the first year of life in children infected/exposed to ZIKV, emphasizing the need for long-term follow-up. Expand
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TLDR
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Congenital brain abnormalities during a Zika virus epidemic in Salvador, Brazil, April 2015 to July 2016
  • M. Kikuti, C. Cardoso, +5 authors G. Ribeiro
  • Medicine
  • Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
  • 2018
TLDR
The magnitude of neurological consequences of the ZIKV epidemic and the limitations of head circumference in accurately identifying children with CBA are highlighted and Gestational symptoms compatible with ZikV infection should be combined with imaging studies for efficient detection of suspect CBAs. Expand
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