Describing the structural robustness landscape of bacterial small RNAs

@inproceedings{Rodrigo2012DescribingTS,
  title={Describing the structural robustness landscape of bacterial small RNAs},
  author={Guillermo Rodrigo and Mario A. Fares},
  booktitle={BMC Evolutionary Biology},
  year={2012}
}
BackgroundThe potential role of RNA molecules as gene expression regulators has led to a new perspective on the intracellular control and genome organization. Because secondary structures are crucial for their regulatory role, we sought to investigate their robustness to mutations and environmental changes.ResultsHere, we dissected the structural robustness landscape of the small non-coding RNAs (sncRNAs) encoded in the genome of the bacterium Escherichia coli. We found that bacterial sncRNAs… CONTINUE READING
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