Describing Kawasaki shock syndrome: results from a retrospective study and literature review

  title={Describing Kawasaki shock syndrome: results from a retrospective study and literature review},
  author={Andrea Taddio and Eleonora Dei Rossi and Lorenzo Monasta and S. Pastore and Alberto Tommasini and Loredana Lepore and Gabriele Bronzetti and Edoardo Marrani and Biancamaria D.’Agata Mottolese and Gabriele Simonini and Rolando Cimaz and Alessandro Ventura},
  journal={Clinical Rheumatology},
Kawasaki shock syndrome (KSS) is a rare manifestation of Kawasaki disease (KD) characterized by systolic hypotension or clinical signs of poor perfusion. The objectives of the study are to describe the main clinical presentation, echocardiographic, and laboratory findings, as well as the treatment options and clinical outcomes of KSS patients when compared with KD patients. This is a retrospective study. All children referred to two pediatric rheumatology units from January 1, 2012, to December… 

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Moderate shock is the main reason for PICU admission in children suffering from Kawasaki disease and these forms can be associated with surprising MODS, hence the need for proper diagnosis and rapid treatment of these unusual severe forms.

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Shock: an unusual presentation of Kawasaki disease

Describing a 5-month-old female infant with severe shock syndrome requiring fluid resuscitation, inotropic support, and PICU admission, and diagnosis retrospectively to have KD complicated by coronary artery aneurysms is described.

Recognition of a Kawasaki Disease Shock Syndrome

Kawasaki disease shock syndrome is associated with more-severe laboratory markers of inflammation and greater risk of coronary artery abnormalities, mitral regurgitation, and prolonged myocardial dysfunction and may be resistant to immunoglobulin therapy and require additional antiinflammatory treatment.

Atypical and incomplete Kawasaki disease.

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Patients who have Kawasaki disease and are admitted to the ICU are at increased risk for intravenous immunoglobulin–refractory disease and may be at risk for development of more severe coronary artery disease.

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