Describing Crouzon and Pfeiffer syndrome based on principal component analysis.


UNLABELLED Crouzon and Pfeiffer syndrome are syndromic craniosynostosis caused by specific mutations in the FGFR genes. Patients share the characteristics of a tall, flattened forehead, exorbitism, hypertelorism, maxillary hypoplasia and mandibular prognathism. Geometric morphometrics allows the identification of the global shape changes within and between… (More)
DOI: 10.1016/j.jcms.2015.02.005


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