Descending respiratory polysynaptic inputs to cervical and thoracic motoneurons diminish during early postnatal maturation in rat spinal cord.

@article{Juvin2005DescendingRP,
  title={Descending respiratory polysynaptic inputs to cervical and thoracic motoneurons diminish during early postnatal maturation in rat spinal cord.},
  author={Laurent Juvin and Didier Morin},
  journal={The European journal of neuroscience},
  year={2005},
  volume={21 3},
  pages={808-13}
}
Isolated brainstem-spinal cord preparations were used to explore the coexistence of a direct and an indirect descending drive from the brainstem respiratory centre to cervical and thoracic respiratory motoneurons in the neonatal Sprague-Dawley rat. Polysynaptic spinal relay pathways from the respiratory centre were suppressed by selectively perfusing the cord with mephenesin (1 mM) or a solution enriched with Ca2+ and Mg2+. At birth, both direct and spinally relayed pathways are functional and… CONTINUE READING

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