Desaturation of isomeric trans-octadecenoic acids by rat liver microsomes.

@article{Mahfouz1980DesaturationOI,
  title={Desaturation of isomeric trans-octadecenoic acids by rat liver microsomes.},
  author={Mohamedain M Mahfouz and Anthony J. Valicenti and Ralph T. Holman},
  journal={Biochimica et biophysica acta},
  year={1980},
  volume={618 1},
  pages={1-12}
}
Desaturation of twelve labeled positional isomers of trans-18 : 1 acids was investigated using enzymes of liver microsomes from essential-fatty-acid-deficient rats. Oleic acid was used as model for comparison and for optimizing the incubation conditions. Each positional isomer desaturated at a unique rate. The trans-6- and trans-13-octadecenoic acids gave… CONTINUE READING