Desaturation and Related Modifications of Fatty Acids1.

  title={Desaturation and Related Modifications of Fatty Acids1.},
  author={John Shanklin and Edgar B Cahoon},
  journal={Annual review of plant physiology and plant molecular biology},
Desaturation of a fatty acid first involves the enzymatic removal of a hydrogen from a methylene group in an acyl chain, a highly energy-demanding step that requires an activated oxygen intermediate. Two types of desaturases have been identified, one soluble and the other membrane-bound, that have different consensus motifs. Database searching for these motifs reveals that these enzymes belong to two distinct multifunctional classes, each of which includes desaturases, hydroxylases, and… CONTINUE READING
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