Dermic peripheral microangiopathy in plasmo-proliferative disorders.

@article{Valds1976DermicPM,
  title={Dermic peripheral microangiopathy in plasmo-proliferative disorders.},
  author={E Francisco Vald{\'e}s and Marco Velasco Herrero and Ignacio Luis Calb and Rocio Elizabeth Jimenez Vazquez},
  journal={Dermatologica},
  year={1976},
  volume={152 6},
  pages={
          340-6
        }
}
Skin biopsy specimens from 12 patients with plasmo-proliferative disease (myeloma and macrogobulinemia) were histopathologically and histochemically examined. In all the cases studied (by a biopsy obtained from the hand) there were alterations in the dermal microvasculature characterized by thickening of the PAS-stained basal membrane, endothelial swelling and proliferation with partial obliteration of the vascular lumen. The lesions were morphologically similar to those found in diabetic and… CONTINUE READING
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