Dermatosis in children with oedematous malnutrition (Kwashiorkor): a review of the literature

@article{Heilskov2014DermatosisIC,
  title={Dermatosis in children with oedematous malnutrition (Kwashiorkor): a review of the literature},
  author={Sofine Heilskov and Maren Jh Rytter and Christian Vestergaard and Andr{\'e} Briend and E Babirekere and Mette Deleuran},
  journal={Journal of the European Academy of Dermatology and Venereology},
  year={2014},
  volume={28}
}
Children with oedematous malnutrition, known as kwashiorkor, may develop a characteristic skin lesion, named ‘Dermatosis of Kwashiorkor’ (DoK). Only a few studies have been concerned with this condition, and the reason for the development of DoK remains unexplained. This study review the existing studies concerning DoK, including its clinical manifestations, histopathology, suggested pathophysiology, current treatment and prognosis for children of the age of 6 months to 5 years. Standardized… 

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References

SHOWING 1-10 OF 71 REFERENCES

The dermatosis associated with kwashiorkor in Basutoland.

  • K. E. Ground
  • Medicine
    Transactions of the Royal Society of Tropical Medicine and Hygiene
  • 1957

The dermatosis of kwashiorkor in young children.

TLDR
When "flaky paint" dermatosis is seen in a malnourished child with edema, it is pathognomonic of the disease kwashiorkor, the other life-threatening form of PEM.

CLINICAL ASPECTS OF THE TREATMENT OF KWASHIORKOR

  • H. Trowell
  • Medicine
    Annals of the New York Academy of Sciences
  • 1954
TLDR
The clinical aspects of kwashiorkor are discussed, which are a study of the disease in young children, among whom the condition is far more common because of their high requirements for protein and allied substances.

Kwashiorkor in African Children in Durban

TLDR
Evidence of a relationship between tuberculous infection and the onset of sarcoidosis is found, and it is suggested that contact with tuberculosis may well be a substantial rather than a minor cause.

Pellagra in African children

  • H. Trowell
  • Medicine
    Archives of disease in childhood
  • 1937
TLDR
No clinical observer who has recorded cases in Africa has been able to agree that it is pellagra, but its interest for English clinicians lies in the points in which it resembles and yet differs from pink disease.

Cystic fibrosis presenting with dermatitis.

TLDR
It is important to consider cystic fibrosis as a possible diagnosis in any infant presenting with a rash and other signs of malnutrition, given the frequent delay in diagnosis, as well as the increased morbidity and mortality associated with protein-energy malnutrition in these patients.

'Peeling paint' dermatitis as a presenting sign of cystic fibrosis.

Acrodermatitis enteropathica-like eruption as the presenting sign of cystic fibrosis – case report and review of the literature

TLDR
It is reported on a patient presenting with refractory dermatitis resembling acrodermatitis enteropathica as the first sign of CF at the age of 4 months, but without pulmonary symptoms, and laboratory findings demonstrated anaemia, hypoproteinaemia and zinc deficiency.

Malnutrition‐Associated Rash of Cystic Fibrosis

TLDR
Rash is a rare presenting sign of cystic fibrosis complicated by protein‐calorie malnutrition and appears to involve a complex interaction among deficiencies of EFAs, zinc, protein, and possibly copper, leading to disordered prostaglandin metabolism or cytokine production, or free radical‐induced damage to cellular membranes due to a lack of nutrient‐derived protective antioxidants.
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