Dermatopontin, a novel player in the biology of the extracellular matrix.

  title={Dermatopontin, a novel player in the biology of the extracellular matrix.},
  author={Osamu Okamoto and Sakuhei Fujiwara},
  journal={Connective tissue research},
  volume={47 4},
Dermatopontin is a widely distributed small molecular weight protein in the extracellular matrix (ECM) and today its homologues are known in five mammals and several invertebrates. The structures of these homologues are relatively well conserved among the species. In the skin, dermatopontin is located mainly on the surface of the collagen fibers. It is found in the conditioned medium and also in the cytoplasm of cultured fibroblasts. Early studies focused on ECM assembly (collagen… CONTINUE READING


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