Dermatology of androgen-related disorders.

  title={Dermatology of androgen-related disorders.},
  author={Paulina A Essah and Edmond P. Wickham and Julia R Nunley and John Edwin Nestler},
  journal={Clinics in dermatology},
  volume={24 4},
Hyperandrogenism in women can be caused by various conditions, the most prevalent of which is polycystic ovary syndrome. Common dermatologic manifestations of hyperandrogenism include hirsutism, acne, acanthosis nigricans, and androgenic alopecia. Hirsute women often have increased activity of 5 alpha-reductase, the enzyme that converts the androgen testosterone to its active metabolite, in hair follicles. Likewise, androgens affect the formation of acne by increasing sebum production from… CONTINUE READING
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