Dermatan sulfate released after injury is a potent promoter of fibroblast growth factor-2 function.

@article{Penc1998DermatanSR,
  title={Dermatan sulfate released after injury is a potent promoter of fibroblast growth factor-2 function.},
  author={S F Penc and Bohdan Pomahac and Thomas Winkler and Robert A. Dorschner and Emily Eriksson and Mark D Herndon and Richard L Gallo},
  journal={The Journal of biological chemistry},
  year={1998},
  volume={273 43},
  pages={28116-21}
}
Proteoglycans have been shown in vitro to bind multiple components of the cellular microenvironment that function during wound healing. To study the composition and function of these molecules when derived from an in vivo source, soluble proteoglycans released into human wound fluid were characterized and evaluated for influence on fibroblast growth factor-2 activity. Immunoblot analysis of wound fluid revealed the presence of syndecan-1, syndecan-4, glypican, decorin, perlecan, and versican… CONTINUE READING

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