Dermatan sulfate inhibition of fibrin-rich thrombus formation in nonhuman primates.

@article{Cadroy1993DermatanSI,
  title={Dermatan sulfate inhibition of fibrin-rich thrombus formation in nonhuman primates.},
  author={Yves Cadroy and Stephen R. Hanson and Laurence A. Harker},
  journal={Arteriosclerosis and thrombosis : a journal of vascular biology},
  year={1993},
  volume={13 8},
  pages={1213-7}
}
Dermatan sulfate (DS), a factor that amplifies plasma heparin cofactor II antithrombin (HCII) activity, has been evaluated in baboons for its relative antithrombotic and antihemostatic effects by use of a model that combines both platelet-rich and fibrin-rich thrombus formation. Thrombus was generated in a two-component thrombogenic device incorporated into… CONTINUE READING