Dermal penetration of bisphenol A in human skin contributes marginally to total exposure.

@article{Demierre2012DermalPO,
  title={Dermal penetration of bisphenol A in human skin contributes marginally to total exposure.},
  author={Anne-Laure Demierre and Ronald Peter and Aurelia Oberli and Martine Bourqui-Pittet},
  journal={Toxicology letters},
  year={2012},
  volume={213 3},
  pages={305-8}
}
Bisphenol A (BPA) is ubiquitous and many exposure scenarios have been described during the last decades. While oral uptake is considered as the major route of exposure, the contribution of skin penetration has been recently discussed. In the present study, the dermal penetration rate of BPA has been determined in human skin in an in vitro test method according to the OECD Test Guideline 428. This analysis resulted in penetration of 8.6% and a total amount of bio-available BPA of 9.3% of the… CONTINUE READING

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