Dermal exposure to jet fuel suppresses delayed-type hypersensitivity: a critical role for aromatic hydrocarbons.

@article{Ramos2007DermalET,
  title={Dermal exposure to jet fuel suppresses delayed-type hypersensitivity: a critical role for aromatic hydrocarbons.},
  author={Gerardo Ramos and Alberto Yairh Lim{\'o}n-Flores and Stephen E. Ullrich},
  journal={Toxicological sciences : an official journal of the Society of Toxicology},
  year={2007},
  volume={100 2},
  pages={415-22}
}
Dermal exposure to military (JP-8) and/or commercial (Jet-A) jet fuel suppresses cell-mediated immune reactions. Immune regulatory cytokines and biological modifiers, including platelet activating factor (PAF), prostaglandin E(2), and interleukin-10, have been implicated in the pathway of events leading to immune suppression. It is estimated that approximately 260 different hydrocarbons are found in jet fuel, and the exact identity of the active immunotoxic agent(s) is unknown. The recent… CONTINUE READING

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