Dermal absorption of chlorpyrifos in human volunteers.

  title={Dermal absorption of chlorpyrifos in human volunteers.},
  author={Wim J A Meuling and Luco C Ravensberg and L. de la Roza and Joop J van Hemmen},
  journal={International archives of occupational and environmental health},
  volume={78 1},
OBJECTIVE The methods and results are described of a study on the dermal absorption of chlorpyrifos (CPF) in humans established via urinary excretion of the metabolite 3,5,6-trichloro-2-pyridinol (TCP). METHODS Two dermal, single, doses of CPF were applied in two study groups (A and B) each comprising three apparently healthy male volunteers who gave their written informed consent. The clinical part of the study was conducted in compliance with the ICH Guideline and the EC principles of good… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 15 extracted citations

The mismeasure of dermal absorption

Journal of Exposure Science and Environmental Epidemiology • 2011
View 4 Excerpts
Highly Influenced

Review of Pesticide Urinary Biomarker Measurements from Selected US EPA Children’s Observational Exposure Studies

International journal of environmental research and public health • 2011
View 4 Excerpts
Highly Influenced

Percutaneous absorption and exposure assessment of pesticides.

Journal of applied toxicology : JAT • 2010
View 1 Excerpt
Highly Influenced


Publications referenced by this paper.
Showing 1-10 of 13 references

Chlorpyrifos: pharmacokinetics in human volunteers.

Toxicology and applied pharmacology • 1984
View 6 Excerpts
Highly Influenced

The in vitro percutaneous penetration of chlorpyrifos

P Griffin, M Payne, E Freedlander, AD Curran, J Cocker
Hum Exp Toxicol • 2000
View 4 Excerpts
Highly Influenced

Oral and dermal absorption of chlorpyrifos: a human volunteer study.

Occupational and environmental medicine • 1999
View 6 Excerpts
Highly Influenced

In vitro and in vivo percutaneous absorption of catechol.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association • 2003
View 1 Excerpt

Conservatism in pesticide exposure assessment.

Regulatory toxicology and pharmacology : RTP • 2000
View 1 Excerpt

Dose excretion study with the fungicide carbendazim in volunteers

WJA Meuling, JJG Opdam, WLAM. de Kort
Methods, measurements and modeling, • 1993
View 2 Excerpts

Similar Papers

Loading similar papers…