Dermal Vγ4(+) γδ T cells possess a migratory potency to the draining lymph nodes and modulate CD8(+) T-cell activity through TNF-α production.

Abstract

A large number of gamma delta T cells (γδ T cells) are located within epithelial tissues including the skin. In mice, epidermal and dermal γδ T cells consist of distinct subsets and have specific roles in cutaneous immune responses. A recent study demonstrated that γδ T cells and cutaneous dendritic cells migrate from the skin to the draining lymph nodes… (More)
DOI: 10.1038/jid.2014.516

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Cite this paper

@article{Nakamizo2015DermalV, title={Dermal Vγ4(+) γδ T cells possess a migratory potency to the draining lymph nodes and modulate CD8(+) T-cell activity through TNF-α production.}, author={Satoshi Nakamizo and Gyohei Egawa and Michio Tomura and Shunsuke Sakai and Soken Tsuchiya and Akihiko Kitoh and Tetsuya Honda and Atsushi Otsuka and Saeko Nakajima and Teruki Dainichi and Hideaki Tanizaki and Masao Mitsuyama and Yukihiko Sugimoto and Kazuhiro Kawai and Yasunobu Yoshikai and Yoshiki Miyachi and Kenji Kabashima}, journal={The Journal of investigative dermatology}, year={2015}, volume={135 4}, pages={1007-1015} }