Dermabrasion for Prophylaxis and Treatment of Actinic Keratoses

  title={Dermabrasion for Prophylaxis and Treatment of Actinic Keratoses},
  author={William P. Coleman and J. Michael Yarborough and Stephen H Mandy},
  journal={Dermatologic Surgery},
background After dermabrasion, patients with actinic keratoses remain free of new lesions for many years. This clinical effect has been alluded to for 40 years in the dermatologic literature. However, there has been no consensus on how long this clinical benefit actually lasts. objective To ascertain the longevity of the beneficial effect of dermabrasion, clinical records of patients who underwent this procedure for treatment of actinic keratosis were reviewed. METHOD. Retrospective review… 
Delayed Wound Healing After Three Different Treatments for Widespread Actinic Keratosis on the Atrophic Bald Scalp
Care has to be taken in patients with widespread actinic keratosis on the atrophic bald scalp when treating the entire surface area regardless of the treatment modality.
Facial resurfacing for nonmelanoma skin cancer prophylaxis.
All 3 modalities demonstrated benefit for AK reduction and skin cancer prophylaxis compared with controls and warrant further study in a larger trial.
The treatment of actinic keratoses.
  • S. Dinehart
  • Medicine
    Journal of the American Academy of Dermatology
  • 2000
A physician should select the best treatment by considering features of the lesion(s) and the patient being treated, and all actinic keratoses cannot be treated in the same manner.
Manual resurfacing and trichloroacetic acid for the treatment of patients with widespread actinic damage. Clinical and histologic observations.
The deeper level of this peel explains the improved cosmetic outcome and greater eradication of actinic keratoses and this treatment is particularly well suited for patients with extensive photodamage and widespread actinic Keratoses.
Optimum Treatment Strategies for Actinic Keratosis (Intraepidermal Squamous Cell Carcinoma)
If a lesion exhibits evidence of possible dermal invasion, such as marked erythema, ulceration, tenderness, bleeding, and especially induration, the physician should always consider performing a biopsy to be certain that the lesion is not an invasive squamous cell carcinoma.
Current perspective on actinic keratosis: a review
Improved agreement among clinicians on AK definition may improve management, and treatments should aim to decrease the risk of KC or facilitate KC diagnosis by reducing the potential for misidentification created when a KC appears in a field of AKs.
Pharmacotherapy of actinic keratosis
The goals of treatment are to eliminate the AKs, minimizing their risk of progression to invasive SCC, while pursuing good cosmetic outcomes and prevention is the most important treatment modality for AKs.
The Actinic Keratosis A Perspective and Update
  • R. Schwartz
  • Medicine
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • 1997
The purpose of this work is to describe the actinic keratosis, a common sun‐induced precancerous neoplasm confined to the epidermis that is the initial manifestation of a continuum of clinical and histologic abnormalities that progresses to invasive squamous cell carcinoma.
Management of benign skin lesions commonly affecting the face: actinic keratosis, seborrheic keratosis, and rosacea
  • J. Brodsky
  • Medicine
    Current opinion in otolaryngology & head and neck surgery
  • 2009
Advances in the understanding and management of three of the more common benign skin lesions affecting the face will be addressed in this review, with a particular emphasis on the most current therapeutic options for each lesion.


Dermabrasion: therapy and prophylaxis of the photoaged face.
Clinical improvement following dermabrasion of photoaged skin correlates with synthesis of collagen I.
Increase in procollagen I mRNA correlated with clinical improvement, ie, reduction in wrinkling, and this improvement correlates strongly with increased collagen I gene expression.
Malignant potential of actinic keratoses and the controversy over treatment. A patient-oriented perspective.
A mathematical model resulting in patient-oriented statistics that can be more easily compared with historical estimates is presented, showing that the average malignant transformation rate for an actinic keratosis is only a fraction of a percent per year.
A clinical and histologic evaluation of the effects of planing of the senile and actinically damaged skin indicates that planing prevents development of precancerous and cancerous lesions of the skin.
Spontaneous remission of solar keratoses: the case for conservative management
There was a 21.8% increase in the total number of solar keratoses in the 1040 people studied in the 12‐month period, due to new lesions forming at the same time as remissions were occurring.
Dermal changes following abrasion.
The purpose of this paper is to report histologic and clinical observations at intervals up to four years, following both therapeutic and experimental abrasion of the skin. Material and Methods
A comparison of the efficacy and safety of Jessner's solution and 35% trichloroacetic acid vs 5% fluorouracil in the treatment of widespread facial actinic keratoses.
The medium-depth peel induced by Jessner's solution and 35% trichloroacetic acid is a useful alternative therapeutic option for widespread facial AK, particularly for poorly compliant patients, because it equals fluorouracil in efficacy while being superior in terms of the convenience of a single application with little associated morbidity.
Actinic cheilitis. Treatment with the carbon dioxide laser
A total of 43 patients with biopsy‐proven actinic cheilitis were treated with the carbon dioxide (CO2) laser, and after follow‐up of at least 10 months, 26 patients thought that the lip was cosmetically improved, and 40thought that the function of thelip was improved or had not changed.
Cryosurgery cure rate of actinic keratoses.
Planing for precancerous skin.
  • E. Epstein
  • Medicine
    A.M.A. archives of dermatology
  • 1956
The difficulty of evaluating abrasion methods of treating cutaneous pathologic entities is concerned with personalities, and some of the advocates of this procedure were so enthusiastic that this modality was introduced into my therapeutic armamentarium.