Deriving multipotent stem cells from mouse spermatogonial stem cells: a new tool for developmental and clinical research.

@article{Rooij2008DerivingMS,
  title={Deriving multipotent stem cells from mouse spermatogonial stem cells: a new tool for developmental and clinical research.},
  author={Dirk G de Rooij and Sefika Canan Mizrak},
  journal={Development},
  year={2008},
  volume={135 13},
  pages={2207-13}
}
In recent years, embryonic stem (ES) cell-like cells have been obtained from cultured mouse spermatogonial stem cells (SSCs). These advances have shown that SSCs can transition from being the stem cell-producing cells of spermatogenesis to being multipotent cells that can differentiate into derivatives of all three germ layers. As such, they offer new possibilities for studying the mechanisms that regulate stem cell differentiation. The extension of these findings to human SSCs offers a route… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 20 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 31 references

Potency of germ cells and role in regenerative medicine

  • K. Nayernia
  • J . Anat .
  • 2008

Biological characteristics of spermatogonial stem cells cultured in conditions for fibroblasts

  • H. M. Hu, F. C. Xu, W. Li, S. H. Wu
  • J . Clin . Rehab . Tiss . Engin . Res .
  • 2007

Similar Papers

Loading similar papers…