Derivatization of carbohydrates for analysis by chromatography; electrophoresis and mass spectrometry.

  title={Derivatization of carbohydrates for analysis by chromatography; electrophoresis and mass spectrometry.},
  author={David J. Harvey},
  journal={Journal of chromatography. B, Analytical technologies in the biomedical and life sciences},
  volume={879 17-18},
Carbohydrates display a large diversity of structures and their analysis presents many obstacles as the result of properties such as isomeric diversity, existence of branched structures and the lack of chromophores or fluorophores. Consequently, many analytical approaches depend on the application of chemical modifications such as hydrolysis or derivative formation. This review covers various aspects of derivatization that are used for such approaches as improving thermal stability and… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 44 extracted citations


Publications referenced by this paper.
Showing 1-10 of 31 references

A Handbook of Derivatives for Mass Spectrometry

  • V. Zaikin, J. M. Halket
  • IM Publications, Chichester
  • 2009
Highly Influential
3 Excerpts

Warren (Eds.), Glycopeptides and Related Compounds: Synthesis, Analysis and Applications, Marcel Dekker Inc

  • S. B. Levery, C. D. in D.G. Large
  • New York,
  • 1997
Highly Influential
4 Excerpts


  • L. R. Ruhaak, E. Steenvoorden, C.A.M. Koeleman, A. M. Deelder
  • Wuhrer, Proteomics 10
  • 2010
1 Excerpt


  • L. Zhang, Y. Xu, +4 authors P. Yang
  • Eur. J. 15
  • 2009


  • J. Tang, Y. Liu, D. Qi, G. Yao, C. Deng
  • Zhang, Proteomics 9
  • 2009


  • L. Royle, M. P. Campbell, +10 authors R. A. Dwek
  • Biochem. 376
  • 2008


  • M. Yodoshi, A. Tani, Y. Ohta, S. Suzuki
  • Chromatogr., A 1203
  • 2008

Rapid Commun

  • S. I. Snovida, H. Perreault
  • Mass Spectrom. 21
  • 2007


  • H.-L. Cheng, P.-J. Pai, G.-R. He, J. Am
  • Mass Spectrom. 18
  • 2007

Methods Molec

  • S. Ma, W. Lau, +4 authors W. Nashabeh
  • Biol. 308
  • 2005

Similar Papers

Loading similar papers…