Derivatization in Mass Spectrometry—8. Soft Ionization Mass Spectrometry of Small Molecules

@article{Zaikin2006DerivatizationIM,
  title={Derivatization in Mass Spectrometry—8. Soft Ionization Mass Spectrometry of Small Molecules},
  author={Vladimir G Zaikin and John M. Halket},
  journal={European Journal of Mass Spectrometry},
  year={2006},
  volume={12},
  pages={115 - 79}
}
This is the first of two reviews devoted to derivatization approaches for “soft” ionization mass spectrometry (fast atom bombardment, matrix assisted laser desorption/ionization, electrospray ionization and atmospheric pressure chemical ionization) and deals, in particular, with small molecules. The principles of the main “soft” ionization mass spectrometric methods as well as the reasons for derivatizing small molecules are briefly described. Derivatization methods for modification of amines… 

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