Derivation of smooth muscle cells with neural crest origin from human induced pluripotent stem cells.

@article{Wang2011DerivationOS,
  title={Derivation of smooth muscle cells with neural crest origin from human induced pluripotent stem cells.},
  author={Aijun Wang and Zhenyu Tang and Xian Chao Li and Yisu Jiang and Danielle An‐Chi Tsou and Song Li},
  journal={Cells, tissues, organs},
  year={2011},
  volume={195 1-2},
  pages={
          5-14
        }
}
The heterogeneity of vascular smooth muscle cells (SMCs) is related to their different developmental origins such as the neural crest and mesoderm. Derivation of SMCs from different origins will provide valuable in vitro models for the investigation of vascular development and diseases. From the perspective of regenerative medicine and tissue engineering, an expandable cell source of SMCs is required for the construction of tissue-engineered blood vessels. In this study, we developed a robust… CONTINUE READING

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