Derivation of human induced pluripotent stem cells for cardiovascular disease modeling.

@article{Narsinh2011DerivationOH,
  title={Derivation of human induced pluripotent stem cells for cardiovascular disease modeling.},
  author={Kamileh Narsinh and Kazim H Narsinh and Joseph C Wu},
  journal={Circulation research},
  year={2011},
  volume={108 9},
  pages={1146-56}
}
The successful derivation of human induced pluripotent stem cells (hiPSCs) by dedifferentiation of somatic cells offers significant potential to overcome obstacles in the field of cardiovascular disease. hiPSC derivatives offer incredible potential for new disease models and regenerative medicine therapies. However, many questions remain regarding the optimal starting materials and methods to enable safe, efficient derivation of hiPSCs suitable for clinical applications. Initial reprogramming… CONTINUE READING

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