Derivation of human embryonic germ cells: an alternative source of pluripotent stem cells.

@article{Turnpenny2003DerivationOH,
  title={Derivation of human embryonic germ cells: an alternative source of pluripotent stem cells.},
  author={L. W. Turnpenny and Sarah J. Brickwood and C Mirella Spalluto and Karen Piper and Iain T. Cameron and David I. Wilson and Neil A Hanley},
  journal={Stem cells},
  year={2003},
  volume={21 5},
  pages={598-609}
}
Based on evidence suggesting similarities to human embryonic stem cells, human embryonic germ (hEG) cells have been advocated as an alternative pluripotent stem cell resource but have so far received limited attention. To redress this imbalance, human fetal gonads were collected for the isolation and culture of primordial germ cells at 7-9 weeks postconception. We provide evidence for the derivation, culture, and differentiation of hEG cells in vitro. This evidence includes the expression of… CONTINUE READING

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