Derivation of distal airway epithelium from human embryonic stem cells.

  title={Derivation of distal airway epithelium from human embryonic stem cells.},
  author={Ali Samadikuchaksaraei and Shahar Cohen and K{\'e}vin Isaac and Helen J. Rippon and Julia M P Polak and Robert C Bielby and Anne E. Bishop},
  journal={Tissue engineering},
  volume={12 4},
The pluripotency of embryonic stem cells (ESC) is offering new opportunities in tissue engineering and cell therapy. We have shown previously that alveolar epithelial cells, specifically type II pneumocytes, can be derived from murine ESC and hypothesized that a similar protocol could be used successfully on human ESC. Undifferentiated human ESC were induced to form embryoid bodies that were transferred into adherent culture conditions and grown in a medium designed for the maintenance of… CONTINUE READING
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