Derivation of a bisphenol A oral reference dose (RfD) and drinking-water equivalent concentration.

@article{Willhite2008DerivationOA,
  title={Derivation of a bisphenol A oral reference dose (RfD) and drinking-water equivalent concentration.},
  author={Calvin C. Willhite and Gwendolyn L Ball and Clifton J McLellan},
  journal={Journal of toxicology and environmental health. Part B, Critical reviews},
  year={2008},
  volume={11 2},
  pages={69-146}
}
Human exposure to bisphenol A (BPA) is due to that found in the diet, and BPA and its metabolites were detected at parts per billion (or less) concentrations in human urine, milk, saliva, serum, plasma, ovarian follicular fluid, and amniotic fluid. Adverse health effects in mice and rats may be induced after parenteral injection or after massive oral doses. Controlled ingestion trials in healthy adult volunteers with 5 mg d16-BPA were unable to detect parent BPA in plasma despite exquisitely… CONTINUE READING
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