Derivation of Multivariate Syndromic Outcome Metrics for Consistent Testing across Multiple Models of Cervical Spinal Cord Injury in Rats

@inproceedings{Ferguson2013DerivationOM,
  title={Derivation of Multivariate Syndromic Outcome Metrics for Consistent Testing across Multiple Models of Cervical Spinal Cord Injury in Rats},
  author={Adam R. Ferguson and Karen-Amanda Irvine and John C Gensel and Jessica L. Nielson and Amity Lin and Johnathan Ly and Mark R. Segal and Rajiv R Ratan and J C Bresnahan and Michael S Beattie},
  booktitle={PloS one},
  year={2013}
}
Spinal cord injury (SCI) and other neurological disorders involve complex biological and functional changes. Well-characterized preclinical models provide a powerful tool for understanding mechanisms of disease; however managing information produced by experimental models represents a significant challenge for translating findings across research projects and presents a substantial hurdle for translation of novel therapies to humans. In the present work we demonstrate a novel 'syndromic… CONTINUE READING