Derivation of 2,3,7,8-TCDD toxic equivalent factors (TEFs) for selected dioxins, furans and PCBs with rainbow trout and rat liver cell lines and the influence of exposure time.

Abstract

The effect of exposure time on the induction of 7-ethoxyresorufin O-deethylase (EROD) by 2,3,7,8,-tetrachlorodibenzo-p-dioxin (TCDD), 2,3,7,8-tetrachlorodibenzofuran (TCDF), and 3,3',4, 4'-tetrachlorobiphenyl (PCB 77) was examined in two liver cell lines: rainbow trout RTL-W1 and rat H4IIE. In RTL-W1, exposure time had no effect on induction EC50s and… (More)

Topics

Cite this paper

@article{Clemons1997DerivationO2, title={Derivation of 2,3,7,8-TCDD toxic equivalent factors (TEFs) for selected dioxins, furans and PCBs with rainbow trout and rat liver cell lines and the influence of exposure time.}, author={Jan Clemons and Darren Dixon and Niels C. Bols}, journal={Chemosphere}, year={1997}, volume={34 5-7}, pages={1105-19} }