Derivation efficiency, cell proliferation, freeze-thaw survival, stem-cell properties and differentiation of human Wharton's jelly stem cells.

@article{Fong2010DerivationEC,
  title={Derivation efficiency, cell proliferation, freeze-thaw survival, stem-cell properties and differentiation of human Wharton's jelly stem cells.},
  author={C A Fong and Arjunan Subramanian and Arijit Biswas and K. Gauthaman and Prarthana Srikanth and Manoor Prakash Hande and Ariff Bongso},
  journal={Reproductive biomedicine online},
  year={2010},
  volume={21 3},
  pages={391-401}
}
Human mesenchymal stem cells (MSC) are non-controversial multipotent stem cells. Their presence in umbilical cord blood (UCB) has been debated in some studies and others report low counts per cord blood unit and poor proliferation rates. On the other hand, Wharton's jelly of human umbilical cords appears to be a rich source of human MSC. This study derived 13 human Wharton's jelly stem cell (WJSC) lines from 13 human umbilical cords (100%) and recovered 4.7 +/- 0.2 x 10(6) live WJSC/cm of cord… CONTINUE READING