Derivation and validation of a composite index of severity in chronic obstructive pulmonary disease: the DOSE Index.

  title={Derivation and validation of a composite index of severity in chronic obstructive pulmonary disease: the DOSE Index.},
  author={R. Jones and G. Donaldson and N. Chavannes and K. Kida and M. Dickson-Spillmann and S. Harding and J. Wedzicha and David Price and M. Hyland},
  journal={American journal of respiratory and critical care medicine},
  volume={180 12},
  • R. Jones, G. Donaldson, +6 authors M. Hyland
  • Published 2009
  • Medicine
  • American journal of respiratory and critical care medicine
  • RATIONALE Chronic obstructive pulmonary disease (COPD) is increasingly recognized as a multicomponent disease with systemic consequences and effects on quality of life. Single measures such as lung function provide a limited reflection of how the disease affects patients. Composite measures have the potential to account for many of the facets of COPD. OBJECTIVES To derive and validate a multicomponent assessment tool of COPD severity that is applicable to all patients and health care settings… CONTINUE READING

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