Derivation and validation of a composite index of severity in chronic obstructive pulmonary disease: the DOSE Index.

@article{Jones2009DerivationAV,
  title={Derivation and validation of a composite index of severity in chronic obstructive pulmonary disease: the DOSE Index.},
  author={Rupert C. M. Jones and Gavin C Donaldson and Niels H. Chavannes and Kozui Kida and Maria Dickson-Spillmann and Samantha Harding and Jadwiga A Wedzicha and David Brendan Price and Michael E. Hyland},
  journal={American journal of respiratory and critical care medicine},
  year={2009},
  volume={180 12},
  pages={
          1189-95
        }
}
RATIONALE Chronic obstructive pulmonary disease (COPD) is increasingly recognized as a multicomponent disease with systemic consequences and effects on quality of life. Single measures such as lung function provide a limited reflection of how the disease affects patients. Composite measures have the potential to account for many of the facets of COPD. OBJECTIVES To derive and validate a multicomponent assessment tool of COPD severity that is applicable to all patients and health care settings… CONTINUE READING
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