Derivation and properties of platelet-derived growth factor-independent rat smooth muscle cells.

@article{Schwartz1990DerivationAP,
  title={Derivation and properties of platelet-derived growth factor-independent rat smooth muscle cells.},
  author={Stephen M Schwartz and L Foy and Daniel F. Bowen-Pope and Russell R. Ross},
  journal={The American journal of pathology},
  year={1990},
  volume={136 6},
  pages={1417-28}
}
The present study reports that smooth muscle cells can be derived from the adult rat aorta without being exposed to serum containing platelet releasate, these cells can also be grown and passaged in medium lacking detectable quantities of platelet-derived growth factor (PDGF). As reported earlier, smooth muscle cells grown from the newborn or injured vessels have a distinctive epithelioid appearance. The platelet factor independent smooth muscle cells have a similar appearance. Unlike the cells… CONTINUE READING