Derepressing Nuclear Receptors for Metabolic Adaptation

@article{Saltiel2011DerepressingNR,
  title={Derepressing Nuclear Receptors for Metabolic Adaptation},
  author={Alan R. Saltiel},
  journal={Cell},
  year={2011},
  volume={147},
  pages={717-718}
}
NCoR is a corepressor of several transcription factors, including the PPAR family of nuclear receptors in fat and muscle. By specifically deleting NCoR in these tissues, Li et al. and Yamamoto et al. now uncover an important role for NCoR in regulating lipid homeostasis through the coordinated control of different nuclear receptors. 
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