Deregulated expression of the RanBP1 gene alters cell cycle progression in murine fibroblasts.

@article{Battistoni1997DeregulatedEO,
  title={Deregulated expression of the RanBP1 gene alters cell cycle progression in murine fibroblasts.},
  author={Alessandra Battistoni and Giulia Guarguaglini and Francesca Degrassi and Carmine Pittoggi and Antonella Palena and Gigliola Di Matteo and Carmela Pisano and Enrico Cundari and Patrizia Lavia},
  journal={Journal of cell science},
  year={1997},
  volume={110 ( Pt 19)},
  pages={
          2345-57
        }
}
RanBP1 is a molecular partner of the Ran GTPase, which is implicated in the control of several processes, including DNA replication, mitotic entry and exit, cell cycle progression, nuclear structure, protein import and RNA export. While most genes encoding Ran-interacting partners are constitutively active, transcription of the RanBP1 mRNA is repressed in non proliferating cells, is activated at the G1/S transition in cycling cells and peaks during S phase. We report here that forced expression… CONTINUE READING

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